Better Sleep

Pain Relief

Decreased Stress

Improved Immunity

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Learn how MDbio products restore your endocannabinoid balance and maximize health


Rated 5.0 out of 5
Based on 6 reviews
Anxiety and stress can affect your mood, sleep and health, making your days and nights more difficult than they need to be. MDcalm™ combines a full-spectrum hemp extract with adaptogens, botanicals and magnesium L-Threonate to calm your body and ease your mind, naturally.
Full Spectrum Hemp Oil, Lavender Flower Extract, Ashwagandha, Mint Leaves Extract, Reishi Mushroom, and Magnesium L-Threonate.
  • One-time

Count: 10

Select Softgel Count

Stress & Anxiety Can Box You In

Stress is an inevitable part of daily life, but too much will impact your health and keep you from enjoying your life. De-stressing can help you cope by supporting balance from within - but sometimes we all need help to do so.


Suggested Use: Adults take 1 softgel daily to promote balanced immune functions.*

Bodyweight and personal metabolism can affect optimal dosing.

Start with one soft gel; increase to maximum 3 gel caps per day, depending on results.*

 *These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to cure or treat any disease.

Supplement Facts


Doctor Formulated

Sustainably Sourced Ingredients

Patient Tested

Broad Spectrum

Non-Intoxicating (non-psychoactive)

Cruelty Free



All the botanicals we source are ultra-pure and are grown in soils nurtured over time by experienced botanical growers.

Organic Full-Spectrum Hemp Extract (aerial parts) Natural source of beneficial phytocannabinoids, terpenes and flavonoids

Lavender Flower Extract.Inhibits the body’s natural fight-or-flight mechanism to create a serene mind while exhibiting no sedative effects.

Ashwagandha. Has properties to calm you down, while also boosting your stamina.

Reishi Mushroom. Works to relax the nervous system and ease mental stress.

Magnesium L-Threonate.blocks the activity of more stimulating neurotransmitters and binds to calming receptors, resulting in a more peaceful, resting state.

Mint Leave Extract.

Our Pillars for a Calm Mind.

Essential Oils

Our essential oils are key to telling your body it’s time to relax. Think of them as the primer to get your body ready for rest and sleep.



Already naturally occurring in your body’s Endocannabinoid system, our full spectrum hemp creates the balance your system needs.



Derived directly from plants, our pure botanicals have been proven for thousands of years to be effective in helping promote less sleepless nights.


It’s Our Ingredients That Make the Difference.


Achieve Lasting Balance & Harmony

With MDcalm™ you’re getting not only the optimal blend of premium, plant-based wellness ingredients to offset the stress of life, but also perhaps the only truly “doctor-developed” and tested alternative to traditional big pharma options to combat life’s daily ups and downs.

MDcalm™ Reviews

Rated 5.0 out of 5
Based on 6 reviews


Commonly asked questions

When should I take MDcalm™ ?

We recommend most customers take MDcalm in the morning for a full day of relief. If you require MDcalm only situationally, we recommend taking 30 minutes prior to that activity to enjoy the benefits of the calming blend.

How do I know how much to take?

As with all medicines, there is no “one size fits all”. We have designed our product to be effective for most people with 1 softgel per serving. It will depend on your own metabolism, and other various internal and external factors. For more information, see our dosing page.

Why did you add Full Spectrum Hemp to MDcalm and what does it do?

Full spectrum hemp contains over 80 different phytocannabinoids (such as CBD, CBN, CBG, ect.) that work together to regulate the various major systems in your body. By decreasing the stress, anxiety and over activity in your central nervous system, full spectrum hemp has been shown to promote a full body calm.

What if I still feel anxious after my first day of use?

This is to be expected! All natural medicines (and most pharmaceuticals for that matter) require a few days to build up in the system. We see the vast majority of users experience a better state of calm by the 3rd day. If you are still not experiencing optimal balance during the day, try increasing your dose. Use our dosing guidelines as a helpful tool.

Will this product make me drowsy?

No! We have specially formulated our calm blend to have all of the relaxing effects, with none of the sedative properties. Think mellow, but productive!

Will this product interfere with my current medications?

As with any new supplement use, you should speak with your doctor if you have any concerns.

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Derived from the flower, lavender has become a household name in calm and relaxation.. Lavender inhibits the body’s natural fight-or-flight mechanism to create a serene mind while exhibiting no sedative effects. There’s a reason this powerful flower is used in almost every spa and relaxation clinic across the world.



Used for its aromatic soothing, as well as internal calming effects, Mint has acted as a gentle muscle relaxant for thousands of years.



The hemp plant contains over 80 different phytochemicals that work together to create a sense of balance and harmony within the body by activating the endocannabinoid system. This system regulates all the major systems in the body, including an overactive nervous system that can send too many signals of stimulation to the brain when not in balance.



A very important tool to create a sense of calm in the body. Magnesium blocks the activity of more stimulating neurotransmitters and binds to calming receptors, resulting in a more peaceful, resting state.



One of the oldest and most storied ingredients we use in our blends, this herb has properties to calm you down, while also boosting your stamina. Used as a great tool to calm the mind, while keeping you moving throughout your day.



The adaptogenic beta-D-glucans and triterpenes in reishi work to relax the nervous system and ease mental stress, creating a relaxed state of focus similar to a meditative state.