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Better Sleep

Pain Relief

Decreased Stress

Improved Immunity

Learn more about our 4 Board-Certified MD founders

Learn how MDbio products restore your endocannabinoid balance and maximize health

MDimmune+

The natural supplement to protect yourself from everyday challenges.

Doctor
fomulated

Patient

tested

Sustainably
sourced

Cruelty

free

Non

intoxicating

Non
GMO

Stay healthy and up your defense

“I have not had one cold or seasonal problem since I started using this!”

— Beth S.

  • Full spectrum hemp
  • Premium plant-based ingredients
  • Hundreds of phytochemicals
  • Doctor-developed optimal blend
  • Tested with real patients
  • Safe alternative pharmaceuticals
  • Not psychoactive
  • Restores balance
  • Supports internal ECS system

Feel protected

The efficacy of MDimmune+ hemp formula has been scientifically researched.

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Real people who tried it say:

  • People are noticing how good my health is! Thanks a lot!
  • While recovering from illness, I experienced immediate benefits.
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Our solutions work with

The endocannabinoid system.

Discovered in in the 1990s, the Endocannabinoid system (ECS) is a sophisticated biological “control system.”

It is a complex matrix of cell receptors, neurotransmitters and enzymes that all work together to maintain homeostasis.

The largest system of biochemical receptors in our body, ECS is made of 3 parts:

Endocannabinoids in our body interact with specific parts of our cells called endocannabinoid receptors. These receptors are found on different types of cells in our body and can cause different reactions when activated. Scientists have studied two of these receptors of importance for the effects of endocannabinoids.

  • Cannabinoid 1 (CB1) Receptors: They are primarily found in the central nervous system, especially in neurons or nerve cells in the brain. THC and anandamide also bind with these receptors.
  • Cannabinoid 2 (CB2) Receptors: Found in the peripheral nervous system and immune cells. They are like tiny keyholes unlocked by molecules called 2-AG. The CB2 receptors can help reduce inflammation and other immune responses.

Endocannabinoids are natural chemicals our bodies make, similar to those found in cannabis plants. Our body produces endocannabinoids when required rather than in advance. The nervous system uses these chemicals to communicate with different body parts. 

Your body can produce these chemicals because they come from fats – everyone has an active ECS system. Dr. Larian outlines the role of an endocannabinoid in regulating nervous impulses: “When these nerves feel that the previous nerve is firing too hard… the extra input sends an endocannabinoid. This extra chemical… …goes backward and tells the nerve, ‘Calm down. You’re working too hard. Go back to your baseline and restart.’” 

Scientists have extensively researched two significant types of endocannabinoids: 

  • The messenger or "bliss" molecule: Arachidonoyl ethanolamide (anandamide or AEA)
  • 2-AG: 2-arachidonoyl glycerol enhances the function of CB1 receptors and is the primary natural molecule that can bind to CB2 receptors.

Enzymes are natural substances our bodies produce to create and break down certain chemicals. For example, when a cell needs to send a message, endocannabinoids are made by breaking down fats with the help of enzymes. After the endocannabinoids do their job, they are removed from the cells by a particular protein and broken down further by other enzymes. Regarding endocannabinoids, two types of enzymes help break them down so they don't stay in our body for too long: 

  • Fatty acid amide hydrolase (FAAH): findings suggest that FAAH has a natural ability to break down anandamide and 2-AG.
  • Monoacylglycerol acid lipase (MAG-L): Once the 2-AG molecule has completed its function, it is taken back into the cells and broken down by an enzyme called MAGL. The body uses the broken-down product to produce other compounds.


Understanding how these enzymes work could help create new treatments for diseases like addiction.

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62 Reviews
Real reviews by real people who take MDimmune
average rating 4.9 out of 5
Based on 62 reviews
  • 5 Stars
    56 Reviews
  • 4 Stars
    6 Reviews
  • 3 Stars
    0 Reviews
  • 2 Stars
    0 Reviews
  • 1 Star
    0 Reviews
100% of reviewers would recommend this product to a friend
Review posted
Reviewed by Marion M.
Verified Buyer
Age Range
55 - 64
Symptoms
  • Immunity
Product Qualities
  • Effective
  • Fast-Acting
  • Helpful
  • Does the Job
Rated 4 out of 5

response

Hi, the first time i took this i felt some virus starting to try to get hold of me, i was sneezing and had the bare beginnings of a scratch throat and was starting to not feel so great. the first day I took one and the second day I took 3 after reading the label better. It worked great! Totally prevented me from being sick all together so that was amazing! Recently I had a bad stomach bug, and it didnt handle that as well. I think it kept any body aches away, it just didnt work on the stomach bug.

Are there any contraindications for this? I am an NP and would love any more info. Really overall love this product but only gave 4 stars due to the stomach bug.

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Review posted
Reviewed by Butler P.
Verified Buyer
Symptoms
  • Immunity
Product Qualities
  • Effective
Rated 4 out of 5

Good Decision!

Ever since I started using these, my colds have been a thing of the past. The best part is that they don't make me nauseous like other medications do!

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Review posted
Reviewed by Sophia Y.
Verified Buyer
Age Range
25 - 34
Symptoms
  • Immunity
Product Qualities
  • Effective
Rated 5 out of 5

People Noticing My Good Health

I've been using this product for about a month now and it's already made such an impact. People are noticing how good my health is! Thanks a lot!

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Ask us anything,

the doctors are in

We put a lot of thought into creating these optimal blends for top conditions. Our team of doctors and experts are happy to answer your questions.

Truthfully, anytime! But we recommend you pop MDimmune+ with a meal. Digesting food gets those natural ingredients on the move faster.

Every body has its own universe. Start with 2 softgels for 3 days, and then adjust depending on how you have felt. If you need an extra softgel with each dose because two wasn’t doing the trick, take 3. If you have been experiencing mild side effects such as grogginess, decrease to 1 softgel per dose. The key to finding a therapeutic dose of MDbio products is through consistency. 

"Full Spectrum" is our way of saying we're embracing all the good stuff from the hemp plant (including trace amounts of THC). Think of it as a team: everyone brings something unique to the table. And just like our bodies have evolved over ages with a built-in system (the “endocannabinoid” system) that touches everything we do, we believe that harnessing the full power of hemp makes the perfect tag team.

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