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Better Sleep

Pain Relief

Decreased Stress

Improved Immunity

Learn more about our 4 Board-Certified MD founders

Learn how MDbio products restore your endocannabinoid balance and maximize health

Join a 10-day health study

and try a doctor developed

product at no cost!

Struggling with sleep, stress, or pain? Join MDbio’s FREE Observational Study (OS) to

try a physician-formulated, plant-based product and share your experience.

Join the OS Program

Join a 10-day health study

and try a doctor developed product at no cost!

Struggling with sleep, stress, or pain? Join MDbio’s FREE Observational Study (OS) to try a physician-formulated, plant-based product and share your experience.

Join the OS Program

Smiling man balancing a jar on his head with hands raised.

More sleep.

Less stress/anxiety.

Reduced pain.

✅ Choose your main concern: sleep, anxiety/stress, or pain

✅ Receive your FREE 10-day supply of MDsleep, MDcalm, or MDrelief

✅ Use the product daily and complete short check-ins every 2 days

Choose your concern

More sleep.

Less stress/anxiety.

Reduced pain.

✅ Choose your main concern: sleep, anxiety/stress, or pain

✅ Receive your FREE 10-day supply of MDsleep, MDcalm, or MDrelief

✅ Use the product daily and complete short check-ins every 2 days

Meet the formulations

Clinically developed. Plant-based. Non-sedating.

Meet the formulations

Clinically Developed. Plant-Based. Non-Sedating.

Image of a sleep supplement bottle with ingredient highlights and benefits listed.
Product image and description of MDcalm botanical blend supplement.

Join a Observational Study

Backed by over 1,000 patient experiences and developed by

physicians specializing in integrative and functional medicine.

Why should you join an Observational study?

Real products. Real results.

These are not placebos — you’ll receive a 10-day product supply backed by clinical use in 1,000+ patients

Finally find sleep, stress/anxiety, and pain support

We believe in our products so strongly that we’re offering them to you completely free to try.

No clinic visits, no strings attached

Participate 100% from home. No obligations, no upsells.

Join a study

Join a Observational Study

Backed by over 1,000 patient experiences and developed by

physicians specializing in integrative and functional medicine.

Why should you join an Observational study?

Real products. Real results.

These are not placebos — you’ll receive a 10-day product supply backed by clinical use in 1,000+ patients

Finally find sleep, stress/anxiety, and pain support

We believe in our products so strongly that we’re offering them to you completely free to try.

No clinic visits, no strings attached

Participate 100% from home. No obligations, no upsells.

Schedule onboarding call

Frequently Asked Questions

How long does the Observational Study last?

Just 10-days. You’ll receive your product in the mail, take your product for 10-days and complete short check-in surveys (less than a minute) every two days.


Do I have to pay for shipping the product to me?

No! Everything is 100% FREE, including shipping.


Is this a clinical trial?

No. This is an observational study — patients take the real product and provide self-reported feedback.


Can I choose the product I get?

Yes — you’ll choose the one that best matches your main concern (sleep, anxiety/stress, or pain).

Frequently Asked Questions

How long does the Observational Study last?

Just 10-days. You’ll receive your product in the mail, take your product for 10-days and complete short check-in surveys (less than a minute) every two days.


Do I have to pay for shipping the product to me?

No! Everything is 100% FREE, including shipping.


Is this a clinical trial?

No. This is an observational study — patients take the real product and provide self-reported feedback.


Can I choose the product I get?

Yes — you’ll choose the one that best matches your main concern (sleep, anxiety/stress, or pain).

Two people having a discussion with text overlay about patient care.