Better Sleep

Pain Relief

Decreased Stress

Improved Immunity

Learn more about our 4 Board-Certified MD founders

Learn how MDbio products restore your endocannabinoid balance and maximize health

The Doctors Brand

Scientifically proven plant medicine.

Scientifically proven plant medicine.

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Find your MDsolution
1,200+ 5-star ratings





All natural, MD-approved alternative to prescription drugs













Plant medicine. Developed by doctors.

Four doctors, one leafy dream: MDbio’s plant-powered remedies are rooted in nature and backed by science.

620-Participant Study

We invested in a clinical trial with 620 participants

Scientifically formulated.

Clinically tested.

We put our products to the test and we’re proud to share the results.

View clinical results

Sleep disturbance

57% reported clinical improvement


60% reported clinical improvement


38% reported clinical improvement

Sense of well-being

14% reported clinical improvement

Experiencing discomfort?

Chances are you’re not alone. Learn what causes your symptoms.

Sleep issues

One out of three people have difficulty going to sleep or staying asleep.

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Body aches & pain

When pain lingers for 12 weeks or more, it’s considered chronic.

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Stress & anxiety

If stress becomes chronic, it takes a serious toll on your health.

Learn more


Immunity is a complex system that relies on a dynamic balance.

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Our community is growing.

Over 1,200 5-star ratings

If you're looking for a natural way to improve your sleep, It’s the way to go.

Recovery from illness was much more pleasant when I used this product.

I’m especially talking to those ladies with menopause! I haven’t slept like this, since I’ve been a teenager!

I definitely felt calmer and more relaxed after taking MDcalm. I even quit smoking while using and that's saying a lot! I slept better, too.

I was needing something to take for the stress of my life. Let me say it’s been so much better since I started using this product.. You have nothing to lose but stress. I sleep better and feel Better .. the trial was Heaven sent

I gave up on sleeping pills about a year ago. Since then, I've been on a quest for a natural solution that could get me to sleep faster and more restfully. I'm so glad I found it.

Satisfaction guaranteed.

Or get a full refund within 30 days

Ask us anything,

the doctors are in

We put a lot of thought into creating these optimal blends for top conditions. Our team of doctors and experts are happy to answer your questions.

Typically, our nature's finest compounds take about 15 to 60 minutes to say "hello." But hey, you're unique! Metabolism, what you had for lunch, and your body's quirks play their part. Sit back, sip a tea, and let nature do its thing.

Our products have been developed using natural botanicals and herbs and therefore there should be no harmful side effects for longer term use of our products. If you have any questions determining if our products are right for you, please ask your doctor.

Pharmaceuticals? They're the heavy metal of the medical world. MDbio products are more acoustic guitar. You might get the occasional mild to moderate side effect like nausea or drowsiness, but nothing too wild. If you do hit a sour note, pause the song and check in with your doctor.

Here's our secret recipe: we mix a dash of science with a pinch of ancient wisdom. No magic, just the best of both worlds working together.

Your body's like a custom-made suit—no one size fits all here. Start with 2 softgels for 3 days, and then adjust depending on how you have felt. If you need an extra softgel with each dose because two wasn’t doing the trick, take 3. If you have been experiencing mild side effects such as grogginess, decrease to 1 softgel per dose. The key to finding a therapeutic dose of MDbio products is through consistency. 

Imagine a bouquet of nature in a tiny softgel. We do our best to make them subtle, but sometimes, nature likes to make a statement. That herbal whisper? It's just our products telling you they're filled to the brim with goodness.

Still Have Questions?

Send us a message. You can expect a response within 48 hours.

Restore balance


Without the psychoactive intoxication, unhealthy dependency, or sedative side effects.

Help your body reclaim its natural balance with plant medicine — without the psychoactive intoxication, unhealthy dependency, or sedative side effects.

Find your solution