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Better Sleep

Pain Relief

Decreased Stress

Improved Immunity

Learn more about our 4 Board-Certified MD founders

Learn how MDbio products restore your endocannabinoid balance and maximize health

2,500+ 5-Star Ratings

Scientifically proven.
Doctor recommended.

Scientifically proven.
Doctor recommended.

America’s leading clinically proven supplements
for better sleep, less anxiety and less pain

America’s leading clinically proven supplements for better sleep, less anxiety and less pain

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 "This research supports the idea of synergism between botanical products".

"Plant-based medications erased weeks from recovery after traumatic healthcare events".

"I'm loving it and find it really really helpful in my day to day."

"Restores balance and improves your quality of life."

Four doctors set out on a
mission to tackle the 4 major
conditions affecting health:
sleep, pain, stress, and immunity.

Find your MDsolution

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MDsleepTM

57% reported less sleep disturbance

  • Improves overall sleep quality
  • Helps to calm the central nervous system and quiet the mind
  • Promotes restful sleep without the morning grogginess
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    57% reported less sleep disturbance

    Botanical

    MDreliefTM

    66% reported less pain

  • Helps relieve general aches and pain
  • Helps to reduce inflammation throughout the body
  • Natural alternative to NSAID pain relievers
  • Learn More

    66% reported less pain

    Botanical

    MDcalmTM

    77% reported feeling less anxious

  • Promotes relaxation and quiets the mind
  • Eases muscular tension
  • Supports healthy mood
  • Learn More

    77% reported feeling less anxious

    Botanical

    MDimmune+TM

  • Supports overall immune health
  • Boosts innate and adaptive immune responses
  • Helps to maintain a healthy respiratory system
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    Scientifically formulated.
    Clinically tested to perfection.

    View clinical results

    We have run the largest clinical trials with 4,000+ participants

    We test and retest until our products are clinically proven. We're proud to share the results.

    • MDsleep
    • MDrelief
    • MDcalm

    Doctor Formulated

    Patient Tested

    Sustainably Sourced

    Cruelty Free

    Non-Intoxicating

    Non-GMO

    Relief Revealed:
    Real Stories,
    Real Results

    With Over 2,500 5-Star Ratings.

    Symptoms

  • Insomnia

  • Drowsiness

  • Irritability

  • 11/08/22

    I’ve tried Trazodone, gabapentin, and dispensary CBD for sleep, and none of those even come close to how well this worked for me, I was absolutely blown away.

    Symptoms

  • Frequent colds and flu

  • Persistent fatigue

  • Inflammation and swelling

  • 11/06/23

    Ever since I started using these, my colds have been a thing of the past. The best part is that they don't make me nauseous like other medications do!

    Symptoms

  • Rheumatoid arthritis

  • Aches and stiffness

  • Irritability

  • 11/08/22

    I took a few days worth for some arthritic pain I was experiencing that flared up after some activity. The product kicked in to the point where I had to realize out of nowhere that my discomfort was gone.

    Symptoms

  • High stress

  • Racing heartbeat

  • Trouble sleeping

  • 23/09/23

    I definitely felt calmer and more relaxed after taking MDcalm. I even quit smoking while using and that's saying a lot! I slept better, too.

    Plant medicine,
    developed by
    Doctors

    Take back control of your health with our powerful, natural supplements—formulated to give you lasting relief without the risks of dependency or mind-altering effects.

    Combining time-honored herbal remedies with cutting-edge scientific research, our solutions offer holistic wellness you can trust to support your body and mind.

    Meet our doctors

    Uniquely synergistic formulations

    Quality, high-potency ingredients

    Top-notch clinical studies

    Join our Partner Program

    Offer the only clinically proven, doctor founded supplements on the market for sleep, stress, inflammation, and immune defense.

    From The Doctor’s Deskblog

    Learn more about chronic health issues, and how MDbio’s natural blends can safely replace or supplement pharmaceutical products.